Disseminated histoplasmosis case study
Histoplasma capsulatum, a ground fungus, can infect humans, normally in endemic areas; the resulting disease can be asymptomatic or it can have a benign development, but in rare cases it can develop into a serious clinical condition and can even be fatal. Its most characteristic initial location is in the lungs, resembling tuberculosis, often accompanied by mediastinitis and an exuberant fibrotic response. The spread of this infection can be caused by the concomitance of another illness that alters the immunological balance. Sometimes such an association is not clear.
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Disseminated histoplasmosis in a domestic feline
Histoplasmosis - Symptoms and causes - Mayo Clinic
Histoplasmosis is an infection caused by breathing in spores of a fungus often found in bird and bat droppings. The infection is most commonly spread when these spores are inhaled after taking to the air, such as during demolition or cleanup projects. Soil contaminated by bird or bat droppings also can spread histoplasmosis, putting farmers and landscapers at a higher risk of the disease. In the United States, histoplasmosis commonly occurs in the Mississippi and Ohio River valleys, though it can occur in other areas, too. Most people with histoplasmosis never develop symptoms and aren't aware they're infected. But for some people — primarily infants and those with compromised immune systems — histoplasmosis can be serious. Treatments are available for even the most severe forms of histoplasmosis.
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Information for Healthcare Professionals about Histoplasmosis
Histoplasmosis is a rare disease caused by inhalation of the fungus Histoplasma capsulatum. It can spread via cerebral circulation to the central nervous system as a manifestation of a disseminated infection; particularly in patients with immune suppression, which can result in isolated ring-enhancing lesions and inflammation in the brain. This paper reviews a single case study of a year-old female diagnosed with disseminated CNS histoplasmosis.
At that time, she was diagnosed with acute bronchitis and treated with bronchodilators, empiric antibiotics, and a short course oral steroid taper. This management did not improve her symptoms, and she has gradually worsened over six months. She reports a pound intentional weight loss over the past year. She denies camping, spelunking, or hunting activities.
27.05.2021 17:45:07 Jeff M.:
Relatively easy but quite educational.